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Recent Publications
- Prognosis Prediction of Facemask With Miniplate Therapy in Patients With Cleft Lip With/Without Palate 2025.05.07CONCLUSION: These four T0 cephalometric variables were identified as predictors for determining the prognosis in FMMP treatment for patients with CL/P.
- Lipoteichoic acid from a canine probiotic strain Lacticaseibacillus rhamnosus possesses anti-biofilm capacity against clinically isolated canine periodontopathic Porphyromonas species 2025.05.04Periodontitis is one of the most prevalent oral infectious diseases in canines which is mainly caused by periodontopathic bacteria such as Porphyromonas spp. Biofilm formation of periodontopathogens is closely related to the development of the disease, as it provides increased resistance against dental medicaments or host immunity. Although we recently demonstrated the anti-biofilm activity of […]
- Long-term assessment of a modified tunneling technique for root coverage in lower anterior gingival recession: a retrospective study 2025.05.02CONCLUSIONS: A modified tunneling technique, utilizing SCTG and a volume-stable collagen matrix, appears to represent a reliable option for the long-term management of GR in the lower anterior region, even in cases involving multiple Miller class III GRs.
- Standard operating procedures for quality control of oral biospecimens at the Korea Oral Biobank Network 2025.05.02CONCLUSIONS: To ensure a stable supply of high-quality biospecimens for researchers, regular QC checks should be carried out according to the SOP following the specifications of the Korea Biobank Network under the Korea Disease Control and Prevention Agency.
- Correlation between newly formed bone and the progression of experimental peri-implantitis with or without alveolar ridge preservation in infected and non-infected teeth: a secondary analysis of a preclinical study 2025.05.02CONCLUSIONS: Within the limitations of this study, we were unable to demonstrate that ARP could improve newly formed bone or primary implant stability. Furthermore, neither ARP nor SH significantly influenced the spontaneous progression of experimental peri-implantitis.
- Ganglioside GT1b prevents selective spinal synapse removal following peripheral nerve injury 2025.04.30After peripheral nerve injury, the structure of the spinal cord is actively regulated by glial cells, contributing to the chronicity of neuropathic pain. However, the mechanism by which peripheral nerve injury leads to synaptic imbalance remains elusive. Here, we use a pH-reporter system and find that nerve injury triggers a reorganization of excitatory synapses that […]
- Volumetric change after maxillary sinus floor elevation using absorbable collagen sponge: a retrospective cohort study 2025.04.29CONCLUSION: : Use of ACS for maxillary sinus elevation resulted in detection of new bone formation in 3D analysis. Clinicians can ensure stable amounts of bone formation by inserting an adequate number of ACSs.
- A customized guide device for single needle arthrocentesis on temporomandibular joint 2025.04.29CONCLUSION: : The customized TMJ injection guide, using ear-based reference points, significantly enhances the accuracy and safety of TMJ arthrocentesis. This innovation is expected to increase the accessibility and effectiveness of TMJ-related treatments for clinicians without specialized TMJ expertise.
- Growth differentiation factor 15: a promising biomarker in oral cancer 2025.04.29Growth differentiation factor 15 (GDF-15), a cytokine within the transforming growth factor-β superfamily, is involved in various malignancies, with implications in oral squamous cell carcinoma (OSCC). Elevated GDF-15 levels are correlated with unfavorable prognosis, tumor progression, and chemotherapy resistance, and the protein has been identified as a potential diagnostic and prognostic biomarker for OSCC. Personalized […]
- Anticancer effects of SH003 and its active component Cucurbitacin D on oral cancer cell lines via modulation of EMT and cell viability 2025.04.29CONCLUSIONS: Taken together, these findings suggest that Cucurbitacin D plays a crucial role mediating the anticancer activity of SH003, particularly via the reversal of EMT and the reduction of migratory and invasive potential of oral cancer cells. This study provides valuable insight into the mechanistic basis of SH003, highlighting its potential as a therapeutic agent […]
- The impact of selcopintide on periodontal regeneration in a class II furcation defect model: a radiographic and histomorphometric analysis 2025.04.24CONCLUSIONS: Within the limitations of this study, both formulations of SCPT demonstrated significant regenerative potential in periodontal tissues, with outcomes comparable to those of EMD treatment, suggesting SCPT's viability as an alternative bioactive agent for periodontal regeneration in class II furcation defects.
- A comparison of stone-based and diamond strip approaches for adjusting proximal contact tightness in zirconia and PFM crowns 2025.04.24CONCLUSIONS: The conventional way of achieving reasonable contact tightness using stones and silicone polishers may be influenced by clinicians' experience. To shorten adjustment time, untrained practitioners can employ diamond strips.
- Exploring the interplay of personality traits, academic burnout, and academic engagement in dental students 2025.04.24CONCLUSIONS: The study underscores the significant role of personality traits, particularly Extraversion, in determining academic burnout and engagement, with emotion regulation often playing a mediating role. The findings of this study indicate that personality traits can be approached in a distinct manner when developing strategies to mitigate burnout and increase engagement among dental students. These […]
- Current evidence on the impact of whitening toothpastes on dental restorative materials: A comprehensive review 2025.04.23CONCLUSIONS: These findings highlight the importance of selecting toothpaste formulations that align with restorative material properties to optimize esthetic results without compromising durability. Although HP formulations show promise in balancing whitening efficacy with surface preservation, their long-term effects require further study. Additionally, continued research is needed to refine the formulations, particularly for charcoal and blue […]
- Self-Powered Oxygen Microbubble Generator for Decontamination of Anaerobic Biofilm-Fouled Bioimplants 2025.04.21Biomedical devices often feature a microgap: confined, minuscule spaces that foster bacterial infiltration and biofilm formation. For instance, peri-implantitis with prevalence rates of 4.7-45% at the patient level is a major complication driven by biofilm infections, characterized by chronic inflammation and implant failure. Anaerobic biofilm residing within the microgap serves as a major source of […]
- Influence of cleaning solutions and hydrothermal aging on the flexural strength and microhardness of resins for additively manufactured definitive fixed restorations 2025.04.18CONCLUSIONS: Resin type, cleaning solution, and aging condition affected the flexural strength and microhardness of AM resins intended for definitive restorations. Regardless of hydrothermal aging, AM-CR had the lowest flexural strength when the methyl ether solvent was used, while cleaning solution type did not affect the strength of AM-UA; AM-CR's strength was lower than AM-UA's […]
- Retrospective Study for Intraoral Approach for Zygomaticomaxillary Complex and Orbital Floor Fracture 2025.04.17CONCLUSION: The intraoral approach for managing OF and ZMC fractures offers a viable alternative to traditional surgical methods, maintaining similar clinical outcomes while potentially reducing the risk of aesthetic and functional complications.
- Rat Sarcoma (RAS)-Protein-Targeting Synthetic Cell-Penetrating Peptide as an Anticancer Biomaterial 2025.04.16Various bioactive materials, including peptides, have become potential candidates for slowing cancer growth and metastasis. Among bioactive peptides, a synthetic cell-penetrating peptide referred to as rat sarcoma (RAS)-binding peptide (RBP) was suggested as a potential entity that targets RAS with high affinity in MDA-MB-231 cancer cells. This RAS binding further inhibits the RAS-rapidly accelerated fibrosarcoma […]
- Factors associated with subjective oral health among older adults aged 65 and over living alone: the role of social capital 2025.04.15CONCLUSIONS: Social capital is significantly associated with the subjective oral health levels of older adults aged 65 and over living alone. This emphasizes the importance of enhancing social capital to mitigate oral health inequalities among socially vulnerable older adults living alone.
- Effect of indirect ultrasonic activation on the root canal obturation with premixed calcium silicate cement: an in vitro study 2025.04.15CONCLUSIONS: Within the limitation of this study, indirect ultrasonic activation of premixed CSC did not affect the void formation but presented higher quantitative leakage. Future research incorporating micro-CT imaging would enable a more precise and comprehensive analysis, providing valuable insights into the root canal obturation with premixed CSCs.