Recent Publications

• Muramyl dipeptide potentiates <em>Staphylococcus aureus</em> lipoteichoic acid-induced nitric oxide production via TLR2/NOD2/PAFR signaling pathways 2024.12.23
  Lipoteichoic acid (LTA) and peptidoglycan (PGN) are considered as key virulence factors of Staphylococcus aureus, which is a representative sepsis-causing Gram-positive pathogen. However, cooperative effect of S. aureus LTA and PGN on nitric oxide (NO) production is still unclear despite the pivotal roles of NO in initiation and progression of sepsis. We here evaluated the […]
• De novo interleukin-10 production primed by Lactobacillus sakei CVL-001 amplifies the immunomodulatory abilities of mesenchymal stem cells to alleviate colitis 2024.12.20
  Mesenchymal stem cells (MSCs) hold therapeutic promise for treating inflammatory bowel disease (IBD) owing to their immunomodulatory properties. Currently, pre-conditioning strategies with several beneficial agents have been applied to enhance the efficacy of MSCs in treating IBDs. Probiotics are increasingly acknowledged as supplemental therapy for IBD; however, their potential benefits in MSCs-based therapy remain largely […]
• Developing institution-specific admission competency criteria for prospective health sciences students 2024.12.19
  CONCLUSIONS: This study demonstrates the feasibility and value of creating institution-specific admission competency models, offering a methodology that aligns with evidence-based mission-driven selection processes. The distinct competencies identified emphasize the need for educational institutions to consider unique institutional and field-specific requirements and move beyond standardized models to enhance the selection of medical students.
• Three-dimensional digital anatomical measurements of pterygoid plates and posterior maxillary region 2024.12.19
  CONCLUSIONS: This 3D digital anatomical study measured key landmarks for maxillary resection. Such measurement has never been reported. This anatomical study provides surgeons with information on the anatomy of the posterior maxilla and allows for safer and more accurate resection of the difficult-to-resect posterior maxilla.
• Performance and durability of additively and subtractively manufactured resin-based onlay restorations after thermomechanical aging 2024.12.19
  CONCLUSIONS: Tested subtractively manufactured composite resin had the lowest occlusal surface wear with the highest fracture resistance and reliability. Additively manufactured resins had lower dimensional stability, while tested resin for additively manufactured definitive restorations had the highest occlusal surface wear.
• Impact of Subjective Masticatory Difficulty on Malnutrition and Frailty in Community-Dwelling Older Adults 2024.12.19
  CONCLUSION: Restoring chewing function and masticatory satisfaction improves not only oral health but also contributes to overall health and promotes healthy aging in older individuals.
• Severe bilateral subcutaneous emphysema after prophylactic treatment: a case report 2024.12.19
  Subcutaneous emphysema is the accumulation of gas or air in loose subcutaneous connective tissue. The use of air-driven handpieces in dental procedures is a common iatrogenic cause of intraoral mucogingival barrier disruption by high-pressure air. This case report describes a 60-year-old woman who underwent prophylactic periodontal treatment with an air-abrasive device and subsequently developed severe […]
• Risk factors for Clonorchis sinensis infections and control measures reinforced with focused interviews 2024.12.19
  Clonorchiosis, a disease that develops following the consumption of raw freshwater fish that harbors Clonorchis sinensis metacercariae, seriously threatens the health of residents in endemic areas. We aimed to assess the level of awareness of liver fluke infections among infected residents and restaurant workers in liver fluke infection-endemic areas. To identify and provide a more […]
• Targeting Age-Related Impaired Bone Healing: ZnO Nanoparticle-Infused Composite Fibers Modulate Excessive NETosis and Prolonged Inflammation in Aging 2024.12.17
  Bone defects present significant challenges in clinical contexts, particularly among the elderly, and are often linked to altered innate immune responses; however, underlying mechanisms remain to be understood. This study investigates immune changes in early bone healing in aged mice, emphasizing the effects of zinc in modulating inflammatory processes. By exploring the role of zinc […]
• Critical Considerations in Calling Disease-Causing <em>EDAR</em> Mutations in Nonsyndromic Oligodontia 2024.12.17
  Background/Objectives: Oligodontia, the absence of six or more teeth excluding third molars, is a rare genetic condition, unlike hypodontia (missing one or more teeth), which is a relatively common human disease. Methods: To identify the genetic etiology of nonsyndromic oligodontia (NSO) families, we performed mutational analysis and investigated the functional effects of identified EDAR mutations. […]
• Long-term assessment of a modified tunneling technique for root coverage in lower anterior gingival recession: a retrospective study 2024.12.16
  CONCLUSIONS: A modified tunneling technique, utilizing SCTG and a volume-stable collagen matrix, appears to represent a reliable option for the long-term management of GR in the lower anterior region, even in cases involving multiple Miller class III GRs.
• The Impact of Membrane Stabilization for Alveolar Ridge Preservation in Periodontally Compromised Extraction Sockets: A Non-Inferiority Randomized Controlled Trial 2024.12.10
  CONCLUSION: ARP with membrane stabilization in periodontally compromised extraction sockets is non-inferior in terms of soft-tissue contour changes to those without membrane fixation.
• Effect of coffee roasting level on tooth discoloration 2024.12.08
  CONCLUSION: The present findings indicate that tooth discoloration is caused by the complex interaction of CGA, melanoidins, and roasting level. Because of the interplay of these factors, medium roasting had the greatest effect on discoloration.
• Overdiagnosis of dental caries in South Korea: a pseudo-patient study 2024.12.05
  CONCLUSION: The study findings indicate that Korean dentists tend to over-diagnose dental caries, which could pose a threat to public health both in Korea and worldwide. Therefore, it is important to carefully consider strategies to improve the correct diagnosis and standard of care for dental caries by private dentists.
• Successful Secondary Reconstruction and Dental Rehabilitation for a Maxillary Bone Defect with Discontinuity after Partial Maxillectomy: A case report 2024.11.29
  Secondary reconstruction of the maxillary defect with discontinuity after partial maxillectomy is extremely challenging due to extensive, severe adhesions between the maxillary sinus membrane and oral mucosa, resulting in no space for the grafted bone and a lack of soft tissue to cover the graft. This case reports a 23-year-old female patient who underwent secondary […]
• A vaccine platform targeting lung-resident memory CD4⁺ T-cells provides protection against heterosubtypic influenza infections in mice and ferrets 2024.11.28
  Lung tissue-resident memory T (T(RM)) cells induced by influenza vaccination are crucial for heterosubtypic immunity upon re-exposure to the influenza virus, enabling rapid and robust responses upon reactivation. To enhance the efficacy of influenza vaccines, we induce the generation of lung T(RM) cells following intranasal vaccination with a commercial influenza vaccine adjuvanted with NexaVant (NVT), […]
• Preliminary study of environmental risk and protective factors during pregnancy for cleft lip with or without palate in the Korean population 2024.11.25
  CONCLUSIONS: The findings of this study may explain the association between environmental factors and CL/P risk.
• Exploring the Interplay Between Senescent Osteocytes and Bone Remodeling in Young Rodents 2024.11.25
  This study identifies senescent osteocytes in the femur and tibia of young rodents and explores their role in bone remodeling. The proximity of osteoclasts to senescent osteocytes was observed, which is a new finding. Cultured osteocytes, sorted using a podoplanin antibody in FACS, exhibited osteocytic characteristics and increased senescence-related genes. Senescent osteocytes secreted cytokines associated […]
• COVID-19 vaccine acceptance and 5C psychological antecedents amid the omicron surge in South Korea and China 2024.11.23
  CONCLUSIONS: This study reveals a substantial disparity in acceptance, psychological antecedents, and predictors of vaccine acceptance between China and South Korea. This importance of understanding contextual factors influencing public vaccine acceptance is emphasized. There is an urgent need for robust vaccination strategies that boost confidence and alleviate constraints to COVID-19 vaccination, which should be tailored […]
• Complete genome sequence of <em>Weissella cibaria</em> strain CXO-01 isolated from Korean saliva 2024.11.22
  We present the genome sequence of Weissella cibaria strain CXO-01, isolated from saliva from one Korean individual and kimchi. The genome consisted of one circular chromosome with a length of 2,371,631 bp, three circular plasmids of 20,579 bp, 4,818 bp, and 4,494 in size. Gene prediction revealed 2,305 genes, 2,157 coding DNA sequences.