Recent Publications

• Unique Dental and Craniofacial Manifestations of Hypoplastic Amelogenesis Imperfecta in a Patient With Prune Belly Syndrome: A Rare Case Report 2025.10.06
  Introduction: Prune belly syndrome (PBS) is a rare congenital disease characterized by hypoplastic abdominal wall muscles, urological abnormalities, and bilateral cryptorchidism. This report describes a rare case of aberrant hypoplastic amelogenesis imperfecta in a patient with PBS. Case Presentation: A 10-year-old boy with PBS presented with difficulties in speech and mastication. Oral and radiological examinations […]
• Assessment of Vertical Magnification Ratios in Digital Panoramic Radiography Using Phantoms: Evaluation of DICOM Metadata and Calibration Consistency 2025.10.06
  CONCLUSIONS: This study demonstrated that many digital panoramic radiography devices apply software-based corrections to achieve a vertical magnification ratio close to 1.0; however, inconsistencies remain across different systems. Measurement accuracy and clinical reliability can be enhanced by standardization of magnification correction methods and improved documentation in product specifications and DICOM headers, which is clinically relevant […]
• Deteriorated oral health and function as risk factors for physical disability and mortality in community-dwelling older adults: a systematic review and meta-analysis 2025.10.06
  CONCLUSIONS: This systematic review revealed that oral health and function, particularly, masticatory ability and the number of teeth, significantly contributed to physical disability and mortality in older adults.
• Conservative surgical management of stage III medication-related osteonecrosis of the jaw in the mandible: A retrospective study with particular emphasis on anterior mandible 2025.10.03
  CONCLUSION: Conservative surgical management may be a viable alternative to extensive resection in stage III MRONJ of the anterior mandible, particularly when aggressive surgical resection is not feasible. Preserving viable bone is essential for bone healing and functional recovery, and thorough intraoperative assessment is crucial for achieving successful treatment outcomes.
• Educational strategies to enhance dental students' social responsibility: a scoping review 2025.10.02
  CONCLUSION: This review identified community-based education as essential for developing dental students' social responsibility, emphasizing the need for structured community engagement programs combined with critical reflection in dental curricula.
• Protein expression of sialolith with antrolith and tonsillolith examined by immunohistochemistry and immunoprecipitation based high performance liquid chromatography 2025.10.01
  Ultrastructural and proteomic analyses have been performed to elucidate the growth mechanism of sialoliths. However, the role of salivary/blood proteins, inflammatory signaling proteins, inflammatory cytokines, and antimicrobial proteins has not been elucidated. This study examined eight sialoliths, one antrolith, and one tonsillolith which underwent radiological, histological, immunohistochemical (IHC), and immunoprecipitation-based high-performance liquid chromatography (IP-HPLC) analyses. […]
• Optimization of the Purification Process for <em>Lactiplantibacillus plantarum</em> Lipoteichoic Acid with Anti-Biofilm Properties against Dental Pathogens 2025.09.28
  Biofilms formed by oral pathogens play a critical role in the initiation and development of various dental diseases by enhancing resistance to dental medicaments. Previously, we reported the potent anti-biofilm activity of Lactobacillus lipoteichoic acid (LTA), a major cell wall component of Gram-positive bacteria, against various dental pathogens. Nevertheless, the practical application of LTA as […]
• The Evaluation of a Deep Learning Approach to Automatic Segmentation of Teeth and Shade Guides for Tooth Shade Matching Using the SAM2 Algorithm 2025.09.27
  Accurate shade matching is essential in restorative and prosthetic dentistry yet remains difficult due to subjectivity in visual assessments. We develop and evaluate a deep learning approach for the simultaneous segmentation of natural teeth and shade guides in intraoral photographs using four fine-tuned variants of Segment Anything Model 2 (SAM2: tiny, small, base plus, and […]
• Pull-out force and fracture load of fully sintered zirconia hybrid abutment-crowns on Ti-base abutments: Surface treatment effects and material comparison 2025.09.27
  CONCLUSIONS: Applying a 10-MDP-containing primer enhanced the pull-out force of hybrid abutment-crowns milled from fully sintered (Y, Nb)-TZP, with or without APA. Implant restorations fabricated from this material and supported by Ti-base abutments exhibited a fracture load comparable to that of LD and PICN restorations.
• Intranasal NS1-truncated live attenuated canine influenza vaccine confers superior protection compared to inactivated vaccine in beagles 2025.09.26
  Canine influenza virus (CIV) H3N2 continues to circulate among companion animals, posing a zoonotic risk due to its potential for cross-species transmission. However, currently available inactivated vaccines offer limited mucosal immunity and suboptimal protection. Here, we developed a novel intranasal live attenuated CIV H3N2 vaccine carrying a truncated nonstructural protein 1 (NS1) gene and evaluated […]
• Accuracy of artificial intelligence-assisted soft tissue landmark identification in serial lateral cephalograms of Class III two-jaw surgery patients 2025.09.23
  CONCLUSIONS: The AI algorithm in this study might be an effective tool for STLI in Lat-Cephs at T1, T2, and T3, despite the presence of brackets, S-PS, fixed retainers, genioplasty, and bone remodeling.
• Triggering mitotic catastrophe by podophyllotoxin induces apoptosis in oral squamous cell carcinoma 2025.09.18
  CONCLUSIONS: This study provides compelling evidence supporting the potential therapeutic significance of inducing MC-mediated apoptosis in OSCC. The results underscore the role of PPT and its derivatives, such as etoposide and teniposide, in targeting rapidly dividing cancer cells through interference with mitotic progression, offering insights into novel therapeutic strategies for oral cancer.
• Unveiling Immune Responses in the Trachea Following Scaffold Implantation in a Mouse Model 2025.09.17
  CONCLUSION: We present findings on immune responses in the trachea, highlighting the immune cells involved in maintaining homeostasis and their disruption following scaffold implantation. These insights could support the development of targeted immunomodulation strategies, thereby improving the integration and clinical application of biomaterials in tracheal reconstruction.
• Effectiveness of Virtual Reality-based Real-time Ergonomics Training on Dental Posture Improvement 2025.09.17
  CONCLUSION: VR-based real-time feedback enhanced ergonomic awareness and posture correction in dental students by providing objective, immediate feedback.
• Caregivers' perceptions, beliefs and behavior influence dental caries experience in children with autism spectrum disorder: A qualitative study 2025.09.15
  CONCLUSIONS: Our findings support that caregivers' perceptions, beliefs and behavior influence dental caries experience in children with ASD which might need the clinicians' consideration.
• Clinical accuracy and responsiveness of 3D software for measuring facial dimensions at altered vertical dimensions 2025.09.12
  CONCLUSIONS: Stationary facial scanners combined with 3D measurement software provided clinically acceptable accuracy for linear facial measurements. The discrete landmark selection method showed slightly better precision compared to the direct point-to-point connection method, particularly for longer distances between facial landmarks.
• Inhibition of salt-inducible kinases resolves autoimmune arthritis by promoting macrophage efferocytosis 2025.09.11
  No abstract
• Gingival margin repositioning using biologically oriented preparation technique and digital workflow in a maxillary esthetic rehabilitation: A clinical report 2025.09.10
  This clinical report describes the management of gingival recession and gingival line asymmetry around fixed partial dentures using the biologically oriented preparation technique (BOPT). By modifying the emergence profile of the restorations through the BOPT and incorporating a digital workflow, a stable and esthetic gingival margin was achieved. The report highlights the procedural steps, advantages, […]
• Artificial Intelligence-Driven Automated Design of Anterior and Posterior Crowns Under Diverse Occlusal Scenarios 2025.09.05
  CONCLUSIONS: Occlusal scenarios influenced the surface deviation and quality of auto-generated anterior and posterior crown designs. DL software produced higher-quality molar designs than CA software.
• Comparison of the effects of total arch intrusion treatment in adolescents and adults: A pilot study 2025.09.04
  CONCLUSIONS: TAI was an effective treatment option to improve the retrognathic profile. The adolescent group showed significantly greater anteroposterior skeletal improvement and profile changes than the adult group with TAI.