1996-2000
포항공과대학교 신경생리학 이학박사
1994-1996
포항공과대학교 신경생리학 이학석사
1990-1994
성균관대학교 제약학 약학사
2003-현재
서울대학교 치의학대학원 교육/연구 조교수, 부교수, 교수
2011-2012
Johns Hopkins School of Medicine 연구 방문연구원
2001-2003
Johns Hopkins School of Medicine 연구 박사후연구원
2013-현재
한국인지과학회 회원, 이사, 부회장 (2013-2017), 회장 (2018)
2003-현재
대한생리학회 회원, 이사
2001-현재
한국뇌신경과학회 회원, 이사
1999-현재
Society for Neuroscience, Regular Member
G-protein coupled receptor 신호에 의한 시냅스 기능 조절 연구
신경세포-신경교세포, 신경세포-외분비세포 상호작용 기전 연구
판단, 동기, 보상행동의 신경회로 조절 연구
신경 및 정신질환의 시냅스 기능 이상 연구
Choi SY and Kim KT. Characterization of Na+ influx mediated by ATP4—activated P2 purinoceptor in PC12 cells. Br J Pharmacol. 1996;118:935-940.
Choi SY, Morales B, Lee HK, and Kirkwood A. Absence of long-term depression in the visual cortex of GAD65 knockout mice. J Neurosci. 2002; 22: 5271-5276.
Choi SY, Chang J, Jiang B, Seol GH, Min SS, Han JS, Shin HS, Gallagher M, Kirkwood A. Multiple receptors coupled to phospholipase C gate long-term depression in visual cortex. J Neurosci. 2005 Dec 7;25(49):11433-43.
Choi SY, Li J, Jo SH, Lee SJ, Oh SB, Kim JS, Lee JH, Park K. Desipramine Inhibits Na+/H+ Exchanger in Human Submandibular Cells. J Dent Res. 2006 Sep;85(9):839-43.
Kim JH, Park SH, Moon YW, Hwang S, Kim D, Jo SH, Oh SB, Kim JS, Jahng JW, Lee JH, Lee SJ, Choi SY*, Park K. Histamine H1 receptor induces cytosolic calcium increase and aquaporin translocation in human salivary gland cells. J Pharmacol Exp Ther. 2009 Aug;330(2):403-12. doi: 10.1124/jpet.109.153023. Epub 2009 May 14.
Oh D, Han S, Seo J, Lee JR, Choi J, Groffen J, Kim K, Cho YS, Choi HS, Shin H, Woo J, Won H, Park SK, Kim SY, Jo J, Whitcomb DJ, Cho K, Kim H, Bae YC, Heisterkamp N, Choi SY*, Kim E*. Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. J Neurosci. 2010 Oct 20;30(42):14134-44. doi: 10.1523/JNEUROSCI.1711-10.2010.
Yang J, Seo J, Nair R, Han S, Jang S, Kim K, Han K, Paik SK, Choi J, Lee S, Bae YC, Topham MK, Prescott SM, Rhee JS, Choi SY*, Kim E*. DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J. 2011 Jan 5;30(1):165-80. doi: 10.1038/emboj.2010.286.
Sim HR, Choi TY, Lee HJ, Kang EY, Yoon S, Han PL, Choi SY*, Baik JH*. Role of dopamine D2 receptors in plasticity of stress-induced addictive behaviours. Nat Commun. 2013;4:1579. doi: 10.1038/ncomms2598.
Lee SY, Park SH, Chung C, Kim J, Choi SY*, Han JS*. Oxytocin protects hippocampal memory and plasticity from uncontrollable stress. Sci Rep. 2015 Dec 21;5:18540. doi: 10.1038/srep18540.
Lee SH, Kim YJ, Choi SY. BMP signaling modulates the probability of neurotransmitter release and readily releasable pools in Drosophila synapses. Biochem Biophys Res Commun. 2016 Oct 21;479(3):440-446. doi: 10.1016/j.bbrc.2016.09.072.
Kang MS, Choi TY, Ryu HG, Lee D, Lee SH, Choi SY*, Kim KT*. Autism-like behavior caused by deletion of vaccinia-related kinase 3 is improved by TrkB stimulation. J Exp Med. 2017 Oct 2;214(10):2947-2966. doi: 10.1084/jem.20160974. Epub 2017 Sep 12.
Choi TY, Lee SH, Kim YJ, Bae JR, Lee KM, Jo Y, Kim SJ, Lee AR, Choi S, Choi LM, Bang SH, Song MR, Chung J, Lee KJ, Kim SH, Park CS, Choi SY. Cereblon maintains synaptic and cognitive function by regulating BK channel. J Neurosci. 2018 Apr 4;38(14):3571-3583. doi: 10.1523/JNEUROSCI.2081-17.2018.
Noh K, Lee H, Choi TY, Joo Y, Kim SJ, Kim H, Kim JY, Jahng JW, Lee S*, Choi SY*, Lee SJ*. Negr1 modulates anxiety- and depression-like behaviors via interaction with the LIF receptor and Lcn-2 expression. Mol Psychiatry.
2019 Aug;24(8):1189-1205. doi: 10.1038/s41380-018-0347-3. Epub 2019 Jan 16.
Kim YJ, Jo Y, Lee YH, Park K, Park HK, Choi SY. Zn2+ stimulates salivary secretions via metabotropic zinc receptor ZnR/GPR39 in human salivary gland cells. Sci Rep. 2019 Nov 27;9(1):17648. doi:10.1038/s41598-019-54173-3.
Han KA, Lee HY, Lim D, Lee C, Rhee JS, Um JW, Choi SY*, Ko J*. PTPσ Controls Presynaptic Organization of Neurotransmitter Release Machinery at Excitatory Synapses. iScience. 2020 May 28;23(6):101203. doi: 10.1016/j.isci.2020.101203.
Lee SH, Zhang Y, Park J, Kim B, Kim Y, Lee SH, Kim GH, Huh YH, Lee CH, Do NY, Lee B, Kim Y, Lee Y, Kim JY, Kang H, Choi SY, Jang S, Li Y, Kim S, Jin C, Parn K, Kim E, Lee Y, Kim H, Kim E, Choi JH, Kim J, Lee KJ*, Choi SY*, Han K*. Haploinsufficiency of Cyfip2 Causes Lithium-responsive Prefrontal Dysfunction. Ann Neurol. 2020 Sep;88(3):526-543. doi: 10.1002/ana.25827.
